Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29777550 | 0.92 | PTPN1 (0.47) | PTPN1MME | |
| SCHEMBL29767979 | 0.91 | CASP3 (0.52) | PTPN1ECE1MDM4TP53 | |
| SCHEMBL30656185 | 0.90 | CASP3 (0.51) | PTPN1REN | |
| SCHEMBL29372762 | 0.90 | PTPN1 (0.50) | PTPN1MMEECE1MDM4TP53 | |
| SCHEMBL30892068 | 0.89 | PTPN1 (0.49) | PTPN1MDM4TP53 | |
| SCHEMBL14787143 | 0.89 | MDM4 (0.47) | MDM4TP53KMT2A | |
| SCHEMBL31564904 | 0.89 | PTPN1 (0.56) | PTPN1REN | |
| SCHEMBL30804341 | 0.88 | MME (0.53) | MMEMDM4TP53KMT2A | |
| SCHEMBL14788960 | 0.88 | MDM4 (0.46) | PTPN1MDM4TP53KMT2A | |
| SCHEMBL30582698 | 0.88 | CASP3 (0.54) | MDM4TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736271-A | Synthesis method of Tirzepatide | 杭州诺泰澳赛诺医药技术开发有限公司 | 2022-07-12 | — | — | CN | disclosed |