Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729934 | 0.80 | DHFR (0.44) | HRH4 | |
| SCHEMBL29730026 | 0.73 | DHFR (0.42) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29729815 | 0.72 | CDK4 (0.50) | MAP4K1 | |
| SCHEMBL29641431 | 0.69 | ITK (0.43) | — | |
| SCHEMBL29729801 | 0.69 | CTSC (0.49) | — | |
| Hydrochloric Acid SCHEMBL29730045 | 0.68 | BRD4 (0.50) | TNK2MAP4K1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29730017 | 0.68 | ALK (0.52) | TNK2MAP4K1CHEK1 | |
| SCHEMBL29730005 | 0.67 | ALK (0.61) | TNK2CHEK1 | |
| SCHEMBL1491632 | 0.67 | HRH4 (0.43) | HRH4HRH2HRH1HRH3 | |
| SCHEMBL22689949 | 0.67 | IRAK4 (0.52) | HRH1HRH3MAP4K1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022131741-A1 | ISOXAZOLIDINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2022-06-23 | — | — | WO | disclosed |