Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28795586 | 0.81 | PDE7A (0.41) | PDE7AHDAC4 | |
| SCHEMBL23668834 | 0.78 | PDE7A (0.37) | PDE7AHDAC4 | |
| SCHEMBL29731944 | 0.78 | PDE7A (0.37) | PDE7AHDAC4 | |
| SCHEMBL23645651 | 0.77 | AKR1B1 (0.36) | PDE7A | |
| SCHEMBL29732212 | 0.72 | — | — | |
| SCHEMBL23645525 | 0.70 | — | — | |
| SCHEMBL23385698 | 0.68 | OXTR (0.41) | — | |
| SCHEMBL29656597 | 0.68 | OXTR (0.41) | — | |
| SCHEMBL23645062 | 0.67 | PDE7A (0.37) | PDE7AHDAC4 | |
| SCHEMBL29732118 | 0.67 | PDE7A (0.37) | PDE7AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805311-B | Spirocyclic indenes | 苏州亚盛药业有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-114805311-A | Spirocyclic indenes | 苏州亚盛药业有限公司 | 2022-07-29 | — | — | CN | disclosed |
| WO-2022156761-A1 | SPIROCYCLIC INDENES | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2022-07-28 | — | — | WO | disclosed |