SCHEMBL29732000

SCHEMBL29732000

[2H]C([2H])([2H])n1cc(Br)cc(Nc2ccc(N3CCN(C(=O)O)C[C@@H]3C)cn2)c1=O

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BTK Q06187 20/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14913137 0.94 BTK (0.42) BTK
SCHEMBL28357589 0.94 BTK (0.42) BTK
SCHEMBL29731936 0.89 GPR119 (0.41) BTK
SCHEMBL14914814 0.84 BTK (0.41) BTK
SCHEMBL14912698 0.82 BTK (0.45) BTK
SCHEMBL29742073 0.82 BTK (0.45) BTK
SCHEMBL14915914 0.82 BTK (0.45) BTK
SCHEMBL14913568 0.82 BTK (0.39) BTK
SCHEMBL25180233 0.82 BTK (0.42) BTK
SCHEMBL29230406 0.82 BTK (0.42) BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4263552-A1 BTK DEGRADER Guangzhou Lupeng Pharmaceutical Company Ltd. (CN) 2023-10-25 — — EP disclosed
WO-2022133184-A1 BTK DEGRADER NEWAVE PHARMACEUTICAL INC. (US) 2022-06-23 — — WO disclosed
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