SCHEMBL29732406

SCHEMBL29732406

CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(C)C)C(C)C)C(C)C)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 12/20 0.51
▸ NPY1R P25929 7/20 0.51
▸ NPY2R P49146 5/20 0.51
▸ NPY5R Q15761 5/20 0.51
▸ FURIN P09958 5/20 0.42
▸ NOD1 Q9Y239 2/20 0.42
▸ CTSD P07339 1/20 0.40
▸ BACE1 P56817 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30456880 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RFURIN
SCHEMBL30339863 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RFURIN
SCHEMBL29732335 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RFURIN
SCHEMBL30148454 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RFURIN
SCHEMBL30945400 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RFURIN
SCHEMBL1527410 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RFURIN
SCHEMBL30305367 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RFURIN
SCHEMBL29799775 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RFURIN
SCHEMBL1527412 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RFURIN
SCHEMBL30945410 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RFURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250277002-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE PEPTILOGICS, INC. 2025-09-04 — — US claimed
US-20250195611-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. 2025-06-19 — — US claimed
US-20240252586-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. 2024-08-01 — — US claimed
EP-4401754-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF Peptilogics, Inc. (US) 2024-07-24 — — EP claimed
EP-4401752-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF Peptilogics, Inc. (US) 2024-07-24 — — EP claimed
CN-118265536-A Engineered antibacterial peptides and uses thereof 肽逻辑公司 2024-06-28 — — CN claimed
US-20230106943-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. 2023-04-06 — — US claimed
US-20230107222-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE PEPTILOGICS, INC. 2023-04-06 — — US claimed
WO-2023044339-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. (US) 2023-03-23 — — WO claimed
WO-2023044423-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. (US) 2023-03-23 — — WO claimed
WO-2023044487-A1 TREATMENT OF LUNG DISEASE OR INJURY USING ENGINEERED ANTIMICROBIAL PEPTIDES PEPTILOGICS, INC. (US) 2023-03-23 — — WO claimed
US-20220332777-A1 Methods and Compositions for Treatment of Antibiotic-Resistant Bacterial Infections UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2022-10-20 — — US claimed
WO-2022173981-A1 INTRAVENOUS ADMINISTRATION OF ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES PEPTILOGICS, INC. (US) 2022-08-18 — — WO claimed
US-20220249599-A1 TREATMENT OF IMPLANTS WITH ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES PEPTILOGICS, INC. 2022-08-11 — — US claimed
US-20250320266-A1 Methods and Compositions for Treatment of Antibiotic-Resistant Bacterial Infections UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2025-10-16 — — US disclosed
US-20250277002-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE PEPTILOGICS, INC. 2025-09-04 — — US disclosed
US-12371463-B2 Methods and compositions for treatment of antibiotic-resistant bacterial infections University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-07-29 — — US disclosed
US-20220332777-A1 Methods and Compositions for Treatment of Antibiotic-Resistant Bacterial Infections UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2022-10-20 — — US disclosed
WO-2022173981-A1 INTRAVENOUS ADMINISTRATION OF ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES PEPTILOGICS, INC. (US) 2022-08-18 — — WO disclosed
US-20220249599-A1 TREATMENT OF IMPLANTS WITH ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES PEPTILOGICS, INC. 2022-08-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195611-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF VIP, SPPL2B, HM13 NPY4R 2434/4885NPY1R 2661/4885NPY2R 2634/4885
US-20220249599-A1 TREATMENT OF IMPLANTS WITH ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES NGLY1, ANPEP, VIP NPY4R 3342/4885NPY1R 2801/4885NPY2R 3431/4885
US-20230106943-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF VIP, SPPL2B, HM13 NPY4R 2434/4885NPY1R 2661/4885NPY2R 2634/4885
US-20250277002-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE NGLY1, PRF1, LNPEP NPY4R 3510/4885NPY1R 3504/4885NPY2R 3813/4885
US-20230107222-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE NGLY1, PRF1, LNPEP NPY4R 3510/4885NPY1R 3504/4885NPY2R 3813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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