SCHEMBL2973244

SCHEMBL2973244

[CH2]C(O)COS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 2/20 0.43
DHODH Q02127 1/20 0.41
GAA P10253 2/20 0.41
CYP2D6 P10635 1/20 0.39
ALDH1A1 P00352 6/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
SIRT5 Q9NXA8 1/20 0.39
CA7 P43166 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70900 0.86 STAT3 (0.46) STAT3DHODHGAACYP2D6ALDH1A1
SCHEMBL140992 0.86 STAT3 (0.46) STAT3DHODHGAACYP2D6ALDH1A1
SCHEMBL1730532 0.86 STAT3 (0.46) STAT3DHODHGAACYP2D6ALDH1A1
SCHEMBL70901 0.86 STAT3 (0.46) STAT3DHODHGAACYP2D6ALDH1A1
SCHEMBL3508141 0.84 STAT3 (0.44) STAT3DHODHGAACYP2D6ALDH1A1
SCHEMBL3508146 0.84 STAT3 (0.44) STAT3DHODHGAACYP2D6ALDH1A1
SCHEMBL3317915 0.84 STAT3 (0.44) STAT3DHODHGAACYP2D6ALDH1A1
SCHEMBL15189067 0.83 STAT3 (0.43) STAT3DHODHGAACYP2D6ALDH1A1
SCHEMBL8172920 0.83 STAT3 (0.43) STAT3DHODHGAACYP2D6ALDH1A1
SCHEMBL8173710 0.83 STAT3 (0.43) STAT3DHODHGAACYP2D6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7777033-B2 Monomer with anti-microbial character, polymer using the same, and manufacturing method thereof MICRO SCIENCE TECH CO., LTD. (KR) 2010-08-17 US claimed
US-20080188655-A1 Monomer With Anti-Microbial Character, Polymer Using The Same, And Manufacturing Method Thereof MICRO SCIENCE TECH CO., LTD. (KR) 2008-08-07 US claimed
WO-2018167269-A1 COMPOUNDS USEFUL IN THE TREATMENT OR PREVENTION OF A PRMT5-MEDIATED DISORDER Argonaut Therapeutics Limited (GB) 2018-09-20 WO disclosed
US-8703289-B2 Organic polymer particles and process for producing the same, magnetic particles for diagnostics, carboxyl group-containing particles and process for producing the same, and probe-bound particles and process for producing the same JSR CORPORATION (JP) 2014-04-22 US disclosed
EP-1837656-B1 Magnetic particles and method for producing the same JSR CORP (JP) 2010-05-19 EP disclosed
US-7713627-B2 Magnetic particles comprising an organic polymer layer and method for producing the same JSR CORPORATION (JP) 2010-05-11 US disclosed
EP-1890147-B1 Organic polymer particles and process for producing the same, magnetic particles for diagnostics, carboxyl group-containing particles and process for producing the same, and probe-bound particles and process for producing the same JSR CORP (JP) 2010-01-27 EP disclosed
EP-1780544-B1 Magnetic particles for diagnostics JSR CORP (JP) 2009-12-09 EP disclosed
EP-1890147-A1 Organic polymer particles and process for producing the same, magnetic particles for diagnostics, carboxyl group-containing particles and process for producing the same, and probe-bound particles and process for producing the same JSR Corporation (JP) 2008-02-20 EP disclosed
EP-1890148-A1 Organic polymer particles and process for producing the same, magnetic particles for diagnostics, carboxyl group-containing particles and process for producing the same, and probe-bound particles and process for producing the same JSR Corporation (JP) 2008-02-20 EP disclosed
US-20070224424-A1 MAGNETIC PARTICLES AND METHOD FOR PRODUCING THE SAME JSR CORPORATION (JP) 2007-09-27 US disclosed
EP-1837656-A1 Magnetic particles and method for producing the same JSR Corporation (JP) 2007-09-26 EP disclosed
US-20070099814-A1 Organic polymer particles and process for producing the same, magnetic particles for diagnostics, carboxyl group-containing particles and process for producing the same, and probe-bound particles and process for producing the same JSR CORPORATION (JP) 2007-05-03 US disclosed
EP-1780544-A1 Magnetic particles for diagnostics JSR Corporation (JP) 2007-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080188655-A1 Monomer With Anti-Microbial Character, Polymer Using The Same, And Manufacturing Method Thereof PCNA, HSF1, TERB1 STAT3 4383/4885DHODH 2130/4885GAA 1005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.