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Sugi Predict / Compounds / SCHEMBL29732555

SCHEMBL29732555

SCHEMBL29732555

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 3/20 0.53
▸ NPY2R P49146 3/20 0.53
▸ NPY4R P50391 3/20 0.53
▸ ACE P12821 2/20 0.52
▸ KISS1R Q969F8 1/20 0.51
▸ ERAP2 Q6P179 3/20 0.50
▸ ERAP1 Q9NZ08 3/20 0.50
▸ LNPEP Q9UIQ6 3/20 0.50
▸ MC4R P32245 2/20 0.50
▸ GHSR Q92847 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30305296 1.00 NPY1R (0.53) NPY1RNPY2RNPY4RACEKISS1R
SCHEMBL30339977 1.00 NPY1R (0.53) NPY1RNPY2RNPY4RACEKISS1R
SCHEMBL30389284 1.00 NPY1R (0.53) NPY1RNPY2RNPY4RACEKISS1R
SCHEMBL29732607 1.00 NPY1R (0.53) NPY1RNPY2RNPY4RACEKISS1R
SCHEMBL30388127 1.00 NPY1R (0.53) NPY1RNPY2RNPY4RACEKISS1R
SCHEMBL29799876 1.00 NPY1R (0.53) NPY1RNPY2RNPY4RACEKISS1R
SCHEMBL30646173 1.00 NPY1R (0.53) NPY1RNPY2RNPY4RACEKISS1R
SCHEMBL30646172 1.00 NPY1R (0.53) NPY1RNPY2RNPY4RACEKISS1R
SCHEMBL29399853 1.00 NPY1R (0.53) NPY1RNPY2RNPY4RACEKISS1R
SCHEMBL30388977 1.00 NPY1R (0.53) NPY1RNPY2RNPY4RACEKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250195611-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. 2025-06-19 — — US claimed
US-20240252586-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. 2024-08-01 — — US claimed
CN-118265536-A Engineered antibacterial peptides and uses thereof 肽逻辑公司 2024-06-28 — — CN claimed
US-20230106943-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. 2023-04-06 — — US claimed
US-20220249599-A1 TREATMENT OF IMPLANTS WITH ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES PEPTILOGICS, INC. 2022-08-11 — — US claimed
US-20250320266-A1 Methods and Compositions for Treatment of Antibiotic-Resistant Bacterial Infections UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2025-10-16 — — US disclosed
US-20250277002-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE PEPTILOGICS, INC. 2025-09-04 — — US disclosed
US-20250195611-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. 2025-06-19 — — US disclosed
US-20240252586-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. 2024-08-01 — — US disclosed
CN-118265536-A Engineered antibacterial peptides and uses thereof 肽逻辑公司 2024-06-28 — — CN disclosed
US-20240115654-A1 INTRAVENOUS ADMINISTRATION OF ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES PEPTILOGICS, INC. 2024-04-11 — — US disclosed
US-20230107222-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE PEPTILOGICS, INC. 2023-04-06 — — US disclosed
US-20230106943-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. 2023-04-06 — — US disclosed
US-20220249599-A1 TREATMENT OF IMPLANTS WITH ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES PEPTILOGICS, INC. 2022-08-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195611-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF VIP, SPPL2B, HM13 NPY1R 2661/4885NPY2R 2634/4885NPY4R 2434/4885
US-20220249599-A1 TREATMENT OF IMPLANTS WITH ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES NGLY1, ANPEP, VIP NPY1R 2801/4885NPY2R 3431/4885NPY4R 3342/4885
US-20240115654-A1 INTRAVENOUS ADMINISTRATION OF ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES IAPP, VIP, NGLY1 NPY1R 2841/4885NPY2R 3413/4885NPY4R 3117/4885
US-20230106943-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF VIP, SPPL2B, HM13 NPY1R 2661/4885NPY2R 2634/4885NPY4R 2434/4885
US-20250277002-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE NGLY1, PRF1, LNPEP NPY1R 3504/4885NPY2R 3813/4885NPY4R 3510/4885
US-20230107222-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE NGLY1, PRF1, LNPEP NPY1R 3504/4885NPY2R 3813/4885NPY4R 3510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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