SCHEMBL2973291

SCHEMBL2973291

Cc1ccc(C2=CCc3cccc(Br)c32)o1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2959467 0.76 KDM4E (0.33) KDM4ENPC1ALDH1A1LMNAGAA
SCHEMBL2973213 0.75 PIK3R1 (0.36) KDM4ENPC1ALDH1A1LMNAHPGD
SCHEMBL6902557 0.74 KDM4E (0.40) KDM4ENPC1ALDH1A1LMNAGAA
SCHEMBL2962748 0.72 ALDH1A1 (0.47) KDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL2971051 0.72 ALDH1A1 (0.39) ALDH1A1
SCHEMBL31383969 0.71 ALDH1A1 (0.34) ALDH1A1
SCHEMBL2960043 0.71 ALDH1A1 (0.34) ALDH1A1
SCHEMBL2970204 0.71 NPC1 (0.33) NPC1ALDH1A1HSD17B10
SCHEMBL2959490 0.70 MAPT (0.39) KDM4ENPC1ALDH1A1LMNAGAA
SCHEMBL2965054 0.70 MAPT (0.39) KDM4ENPC1ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 KDM4E 2177/4885NPC1 4083/4885ALDH1A1 4332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.