SCHEMBL29733295

SCHEMBL29733295

C=CC(=O)Oc1cccc2cc3cc4cc5ccccc5cc4cc3cc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TYMS P04818 1/20 0.44
▸ THRB P10828 3/20 0.43
▸ THRA P10827 1/20 0.43
▸ HSD17B10 Q99714 6/20 0.42
▸ ALDH1A1 P00352 5/20 0.42
▸ KDM4E B2RXH2 5/20 0.42
▸ KMT2A Q03164 5/20 0.42
▸ MEN1 O00255 4/20 0.42
▸ HPGD P15428 4/20 0.42
▸ MAPT P10636 3/20 0.42
▸ MAPK1 P28482 2/20 0.42
▸ GAA P10253 2/20 0.42
▸ EGFR P00533 1/20 0.42
▸ TP53 P04637 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ PKM P14618 1/20 0.42
▸ ALOX15 P16050 1/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ JAK1 P23458 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29733364 1.00 TYMS (0.44) TYMSTHRBTHRAHSD17B10ALDH1A1
SCHEMBL29733319 1.00 TYMS (0.44) TYMSTHRBTHRAHSD17B10ALDH1A1
SCHEMBL561617 0.98 TYMS (0.45) TYMSTHRBTHRAHSD17B10ALDH1A1
SCHEMBL27722932 0.95 TYMS (0.43) TYMSTHRBTHRAHSD17B10ALDH1A1
SCHEMBL17102366 0.88 TYMS (0.42) TYMSTHRBTHRAHSD17B10ALDH1A1
Acrylic Acid Ethyl Ester SCHEMBL5443556 0.88 THRB (0.45) TYMSTHRBTHRAHSD17B10ALDH1A1
SCHEMBL15302774 0.87 TYMS (0.48) TYMSTHRBTHRAHSD17B10ALDH1A1
Phosphine SCHEMBL18422864 0.87 TYMS (0.41) TYMSTHRBTHRAHSD17B10ALDH1A1
SCHEMBL15302365 0.84 TYMS (0.44) TYMSTHRBTHRAHSD17B10ALDH1A1
SCHEMBL5449463 0.84 TSHR (0.51) THRBTHRAALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355112-A Hydrogel particles as feeder cells and as synthetic antigen presenting cells 弹弓生物科学公司 2024-07-16 — — CN claimed
EP-4267708-B1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS INFINEUM INT LTD (GB) 2025-07-02 — — EP disclosed
US-12281203-B2 Thermally responsive brush polymers having a copolymer backbone and copolymer arms INFINEUM INTERNATIONAL LIMITED (GB) 2025-04-22 — — US disclosed
US-20240309155-A1 Thermally Responsive Brush Polymers Having a Copolymer Backbone and Copolymer Arms INFINEUM INTERNATIONAL LIMITED (GB) 2024-09-19 — — US disclosed
EP-4267708-A1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS Infineum International Limited (GB) 2023-11-01 — — EP disclosed
CN-116981758-A Thermally responsive brush polymers having a copolymer backbone and copolymer arms 英菲诺姆国际有限公司 2023-10-31 — — CN disclosed
WO-2022136384-A1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-30 — — WO disclosed
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