Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 2/20 | 0.40 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29734464 | 1.00 | MGLL (0.49) | MGLLALDH1A1NR3C2GAAMAPT | |
| SCHEMBL22491442 | 1.00 | MGLL (0.49) | MGLLALDH1A1NR3C2GAAMAPT | |
| SCHEMBL22491464 | 1.00 | MGLL (0.49) | MGLLALDH1A1NR3C2GAAMAPT | |
| SCHEMBL22491359 | 0.96 | MGLL (0.48) | MGLLALDH1A1NR3C2GAAMAPT | |
| SCHEMBL22773232 | 0.96 | MGLL (0.48) | MGLLALDH1A1NR3C2GAAMAPT | |
| SCHEMBL22491350 | 0.96 | MGLL (0.48) | MGLLALDH1A1NR3C2GAAMAPT | |
| SCHEMBL29734671 | 0.96 | MGLL (0.48) | MGLLALDH1A1NR3C2GAAMAPT | |
| SCHEMBL22491335 | 0.95 | MGLL (0.53) | MGLLALDH1A1NR3C2NR3C1PGR | |
| SCHEMBL22773251 | 0.95 | MGLL (0.53) | MGLLALDH1A1NR3C2NR3C1PGR | |
| SCHEMBL22491364 | 0.95 | MGLL (0.53) | MGLLALDH1A1NR3C2NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717477-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2022-07-20 | — | — | EP | claimed |
| EP-3717477-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2022-07-20 | — | — | EP | disclosed |