Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 9/20 | 0.45 |
| ▸ | PGR | P06401 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29734473 | 1.00 | MGLL (0.54) | MGLLNR3C2NR3C1PGRMAPT | |
| SCHEMBL22491402 | 1.00 | MGLL (0.54) | MGLLNR3C2NR3C1PGRMAPT | |
| SCHEMBL22491367 | 1.00 | MGLL (0.54) | MGLLNR3C2NR3C1PGRMAPT | |
| SCHEMBL29734515 | 1.00 | MGLL (0.54) | MGLLNR3C2NR3C1PGRMAPT | |
| SCHEMBL22491370 | 1.00 | MGLL (0.54) | MGLLNR3C2NR3C1PGRMAPT | |
| SCHEMBL22491341 | 0.96 | MGLL (0.56) | MGLLNR3C2NR3C1PGRMAPT | |
| SCHEMBL29734397 | 0.96 | MGLL (0.56) | MGLLNR3C2NR3C1PGRMAPT | |
| SCHEMBL22491416 | 0.96 | MGLL (0.56) | MGLLNR3C2NR3C1PGRMAPT | |
| SCHEMBL22491384 | 0.96 | MGLL (0.56) | MGLLNR3C2NR3C1PGRMAPT | |
| SCHEMBL22491338 | 0.94 | MGLL (0.49) | MGLLNR3C2NR3C1PGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717477-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2022-07-20 | — | — | EP | disclosed |