Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22491401 | 1.00 | MGLL (0.50) | MGLLALDH1A1MAPTPOLBNR3C2 | |
| SCHEMBL22491358 | 1.00 | MGLL (0.50) | MGLLALDH1A1MAPTPOLBNR3C2 | |
| SCHEMBL29734507 | 1.00 | MGLL (0.50) | MGLLALDH1A1MAPTPOLBNR3C2 | |
| SCHEMBL22491356 | 1.00 | MGLL (0.50) | MGLLALDH1A1MAPTPOLBNR3C2 | |
| SCHEMBL22491372 | 0.97 | MGLL (0.50) | MGLLALDH1A1MAPTPOLBNR3C2 | |
| SCHEMBL29734631 | 0.97 | MGLL (0.50) | MGLLALDH1A1MAPTPOLBNR3C2 | |
| SCHEMBL29734348 | 0.97 | MGLL (0.50) | MGLLALDH1A1MAPTPOLBNR3C2 | |
| SCHEMBL22491369 | 0.97 | MGLL (0.50) | MGLLALDH1A1MAPTPOLBNR3C2 | |
| SCHEMBL22491325 | 0.97 | MGLL (0.50) | MGLLALDH1A1MAPTPOLBNR3C2 | |
| SCHEMBL29734495 | 0.97 | MGLL (0.50) | MGLLALDH1A1MAPTPOLBNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717477-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2022-07-20 | — | — | EP | claimed |