Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 12/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22491519 | 1.00 | MGLL (0.51) | MGLLNR3C2NR3C1GAAALDH1A1 | |
| SCHEMBL22491497 | 0.88 | NR3C2 (0.51) | MGLLNR3C2NR3C1GAAALDH1A1 | |
| SCHEMBL22491589 | 0.81 | MGLL (0.51) | MGLLNR3C2NR3C1GAAALDH1A1 | |
| SCHEMBL29734625 | 0.81 | MGLL (0.51) | MGLLNR3C2NR3C1GAAALDH1A1 | |
| SCHEMBL22491374 | 0.80 | MGLL (0.49) | MGLLNR3C2NR3C1GAAALDH1A1 | |
| SCHEMBL29734502 | 0.80 | MGLL (0.49) | MGLLNR3C2NR3C1GAAALDH1A1 | |
| SCHEMBL29734532 | 0.80 | MGLL (0.51) | MGLLNR3C2NR3C1GAAALDH1A1 | |
| SCHEMBL22491361 | 0.80 | MGLL (0.51) | MGLLNR3C2NR3C1GAAALDH1A1 | |
| SCHEMBL22491368 | 0.78 | MGLL (0.49) | MGLLNR3C2NR3C1GAAALDH1A1 | |
| SCHEMBL29734501 | 0.78 | MGLL (0.49) | MGLLNR3C2NR3C1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717477-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2022-07-20 | — | — | EP | disclosed |