Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 11/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 11/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26921066 | 1.00 | IRAK4 (0.39) | IRAK4LPLLIPGEGFRIDO1 | |
| SCHEMBL29037924 | 0.90 | IRAK4 (0.37) | IRAK4LPLLIPGEGFRIDO1 | |
| SCHEMBL26920488 | 0.89 | LPL (0.38) | IRAK4LPLLIPGEGFRIDO1 | |
| SCHEMBL29734960 | 0.89 | LPL (0.38) | IRAK4LPLLIPGEGFRIDO1 | |
| SCHEMBL30847373 | 0.88 | IRAK4 (0.39) | IRAK4LPLLIPGEGFRIDO1 | |
| SCHEMBL19836335 | 0.88 | IRAK4 (0.39) | IRAK4LPLLIPGEGFRIDO1 | |
| SCHEMBL22125608 | 0.81 | LPL (0.38) | IRAK4LPLLIPGEGFRIDO1 | |
| SCHEMBL13028373 | 0.80 | DYRK1A (0.42) | IRAK4LPLLIPGEGFRIDO1 | |
| SCHEMBL29520198 | 0.80 | DYRK1A (0.42) | IRAK4LPLLIPGEGFRIDO1 | |
| SCHEMBL29729448 | 0.79 | IRAK4 (0.35) | IRAK4LPLLIPGEGFRIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022167682-A1 | AZABICYCLIC SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2022-08-11 | — | — | WO | disclosed |