SCHEMBL29736280

SCHEMBL29736280

CC(C)C[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(C)C)[C@@H](C)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 3/20 0.46
▸ RXFP1 Q9HBX9 1/20 0.46
▸ TFPI P10646 1/20 0.45
▸ FURIN P09958 2/20 0.44
▸ VIPR2 P41587 1/20 0.44
▸ OPRL1 P41146 3/20 0.43
▸ NPBWR1 P48145 1/20 0.43
▸ PRSS1 P07477 1/20 0.43
▸ NPY1R P25929 2/20 0.43
▸ NPY2R P49146 2/20 0.43
▸ NPY4R P50391 2/20 0.43
▸ NPY5R Q15761 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29625291 0.91 OPRL1 (0.50) TFPIOPRL1
SCHEMBL29625292 0.89 OPRL1 (0.50) RXFP1TFPIOPRL1
SCHEMBL29939729 0.89 TFPI (0.55) IL23RRXFP1TFPIVIPR2
SCHEMBL29808495 0.88 NPY4R (0.51) IL23RTFPINPBWR1NPY1RNPY2R
SCHEMBL28518994 0.88 TFPI (0.54) RXFP1TFPIVIPR2NPY1RNPY2R
SCHEMBL30431331 0.87 VIPR2 (0.53) RXFP1TFPIVIPR2
SCHEMBL31742547 0.87 TFPI (0.58) IL23RTFPINPBWR1NPY1RNPY2R
SCHEMBL30681588 0.87 VIPR2 (0.49) IL23RTFPIVIPR2NPY2R
SCHEMBL29532003 0.86 NPY4R (0.47) IL23RTFPINPBWR1NPY1RNPY2R
SCHEMBL31433335 0.86 IL23R (0.48) IL23ROPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11365217-B2 Peptides for treating telomere dysfunction-associated diseases and uses thereof HANGZHOU DUANLI BIOTECHNOLOGY COMPANY LIMITED (CN) 2022-06-21 — — US disclosed
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