Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.60 |
| ▸ | JAK1 | P23458 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684641 | 0.90 | TYK2 (0.46) | TYK2JAK1 | |
| SCHEMBL29740101 | 0.87 | TYK2 (0.46) | TYK2JAK1 | |
| SCHEMBL29686415 | 0.86 | TYK2 (0.46) | TYK2JAK1 | |
| SCHEMBL24498088 | 0.84 | TYK2 (0.82) | TYK2JAK1KCNH2JAK2 | |
| SCHEMBL29685167 | 0.84 | TYK2 (0.82) | TYK2JAK1KCNH2JAK2 | |
| SCHEMBL29685259 | 0.84 | TYK2 (0.45) | TYK2JAK1 | |
| SCHEMBL30385385 | 0.84 | TYK2 (0.44) | TYK2JAK1 | |
| SCHEMBL29685477 | 0.79 | TYK2 (0.39) | TYK2JAK1KCNH2 | |
| SCHEMBL29685307 | 0.77 | TYK2 (0.35) | TYK2JAK1 | |
| SCHEMBL30490252 | 0.76 | JAK2 (0.55) | TYK2JAK1KCNH2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |