Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 5/20 | 0.55 |
| ▸ | TYK2 | P29597 | 18/20 | 0.53 |
| ▸ | JAK1 | P23458 | 8/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | STAT3 | P40763 | 3/20 | 0.51 |
| ▸ | JAK3 | P52333 | 2/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724634 | 0.88 | TYK2 (0.49) | JAK2TYK2JAK1KCNH2 | |
| SCHEMBL30185827 | 0.87 | JAK2 (0.67) | JAK2TYK2JAK1KCNH2STAT3 | |
| SCHEMBL26122361 | 0.86 | JAK2 (0.59) | JAK2TYK2JAK1KCNH2STAT3 | |
| SCHEMBL29686374 | 0.86 | JAK2 (0.59) | JAK2TYK2JAK1KCNH2STAT3 | |
| SCHEMBL30963331 | 0.85 | TYK2 (0.68) | JAK2TYK2JAK1KCNH2STAT3 | |
| SCHEMBL30490068 | 0.85 | TYK2 (0.46) | JAK2TYK2JAK1KCNH2 | |
| SCHEMBL30490080 | 0.84 | TYK2 (0.49) | TYK2JAK1KCNH2 | |
| SCHEMBL30490253 | 0.83 | TYK2 (0.47) | JAK2TYK2JAK1 | |
| SCHEMBL29686455 | 0.82 | JAK2 (0.82) | JAK2TYK2JAK1STAT3JAK3 | |
| SCHEMBL26117174 | 0.82 | JAK2 (0.82) | JAK2TYK2JAK1STAT3JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |