SCHEMBL29739948

SCHEMBL29739948

C=CSC[C@H](NC(=O)OC(C)(C)C)C(=O)OCC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.65
CYP1A2 P05177 1/20 0.64
CYP2C9 P11712 1/20 0.64
CYP2C19 P33261 1/20 0.64
HTT P42858 1/20 0.64
ALDH1A1 P00352 3/20 0.52
MAPT P10636 3/20 0.52
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
PKM P14618 1/20 0.48
HPGD P15428 1/20 0.48
ALOX12 P18054 1/20 0.48
CTSK P43235 8/20 0.41
CTSS P25774 4/20 0.41
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
PPARG P37231 2/20 0.38
PPARA Q07869 2/20 0.38
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28943389 1.00 SMN1; SMN2 (0.65) SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT
SCHEMBL29739836 0.89 SMN1; SMN2 (0.51) SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT
SCHEMBL28765827 0.89 SMN1; SMN2 (0.51) SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT
SCHEMBL12438545 0.87 CYP1A2 (0.72) SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT
SCHEMBL22792779 0.84 PPARA (0.51) SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT
SCHEMBL13138386 0.84 CYP1A2 (0.72) SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT
SCHEMBL8070420 0.81 SMN1; SMN2 (0.62) SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT
SCHEMBL13950543 0.81 SMN1; SMN2 (0.62) SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT
SCHEMBL12934327 0.81 CYP1A2 (0.77) SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT
SCHEMBL16626925 0.81 CYP1A2 (0.64) SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685330-B Process for producing thio-ethylene compound 华南理工大学 2024-09-10 CN disclosed
CN-114685330-A Process for producing mercaptoethylene compound 华南理工大学 2022-07-01 CN disclosed