Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 9/20 | 0.40 |
| ▸ | TYK2 | P29597 | 9/20 | 0.40 |
| ▸ | JAK2 | O60674 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28839029 | 1.00 | JAK1 (0.40) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL29739841 | 0.90 | JAK1 (0.42) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL28839008 | 0.90 | JAK1 (0.42) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL30490285 | 0.88 | TYK2 (0.41) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL24497957 | 0.87 | TYK2 (0.42) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL30846542 | 0.87 | TYK2 (0.42) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL29739673 | 0.87 | JAK1 (0.41) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL28838871 | 0.87 | JAK1 (0.41) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL28839791 | 0.86 | JAK1 (0.40) | JAK1TYK2JAK2KCNH2KIT | |
| SCHEMBL29739920 | 0.86 | JAK1 (0.40) | JAK1TYK2JAK2KCNH2KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |