Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1766512 | 1.00 | AKR1C2 (0.48) | AKR1C2AKR1C1IRAK4MAPTMEN1 | |
| SCHEMBL29740333 | 1.00 | AKR1C2 (0.48) | AKR1C2AKR1C1IRAK4MAPTMEN1 | |
| SCHEMBL28795297 | 0.93 | AKR1C2 (0.53) | AKR1C2AKR1C1IRAK4MAPTMEN1 | |
| SCHEMBL13508179 | 0.89 | LMNA (0.43) | AKR1C2AKR1C1MAPTMEN1KMT2A | |
| SCHEMBL13508178 | 0.89 | IRAK4 (0.45) | AKR1C2AKR1C1IRAK4MAPTMEN1 | |
| SCHEMBL1766426 | 0.86 | MAPT (0.41) | AKR1C2AKR1C1IRAK4MAPTMEN1 | |
| SCHEMBL29111961 | 0.85 | AKR1C2 (0.46) | AKR1C2AKR1C1IRAK4MAPTMEN1 | |
| SCHEMBL29740334 | 0.83 | MAPT (0.41) | MAPTMEN1KMT2AXBP1NPSR1 | |
| SCHEMBL1766680 | 0.83 | MAPT (0.41) | MAPTMEN1KMT2AXBP1NPSR1 | |
| SCHEMBL3211887 | 0.83 | IRAK4 (0.49) | AKR1C2AKR1C1IRAK4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656373-B | Cyano-substituted benzamide compound and application thereof | 南通泰禾化工股份有限公司 | 2025-04-15 | — | — | CN | disclosed |
| WO-2022135447-A1 | CYANO-SUBSTITUTED BENZAMIDE COMPOUND AND APPLICATION THEREOF | 南通泰禾化工股份有限公司 | 2022-06-30 | — | — | WO | disclosed |
| CN-114656373-A | Cyano-substituted benzamide compound and application thereof | 南通泰禾化工股份有限公司 | 2022-06-24 | — | — | CN | disclosed |