Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782732 | 1.00 | CYP11B1 (0.37) | CYP11B1CYP11B2KMT2AACHEKDM1A | |
| SCHEMBL23782896 | 0.80 | CYP11B1 (0.40) | CYP11B1CYP11B2KMT2AACHE | |
| SCHEMBL23782944 | 0.78 | AR (0.37) | CYP11B1CYP11B2KMT2AACHE | |
| SCHEMBL23783045 | 0.73 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL29741180 | 0.73 | KMT2A (0.43) | CYP11B1CYP11B2KMT2AACHE | |
| SCHEMBL18629818 | 0.72 | CYP11B1 (0.37) | CYP11B1CYP11B2KMT2A | |
| SCHEMBL22889706 | 0.72 | CYP11B1 (0.37) | CYP11B1CYP11B2KMT2A | |
| SCHEMBL10287385 | 0.69 | UGT2B17 (0.42) | CYP11B1CYP11B2ACHE | |
| SCHEMBL18629715 | 0.69 | CYP11B1 (0.37) | CYP11B1CYP11B2 | |
| SCHEMBL23782933 | 0.69 | CYP11B2 (0.33) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155419-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | ESCAPE Bio, Inc. (US) | 2022-07-21 | — | — | WO | disclosed |