SCHEMBL297423

SCHEMBL297423

Cc1cc(C)c([Si](Cl)(Cl)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 9/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
MEN1 O00255 1/20 0.31
MPI P34949 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
NUDT1 P36639 1/20 0.31
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1314789 0.82 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL4464617 0.82 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL20815388 0.80 RAPGEF4 (0.38) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL1314506 0.80 RAPGEF4 (0.38) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL1314874 0.80 RAPGEF4 (0.38) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL13295957 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL13296036 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL15410543 0.72 IDO1 (0.33) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL1316132 0.72 KDM4E (0.32) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL1314938 0.72 KDM4E (0.32) RAPGEF4ALDH1A1KDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112652756-B In-situ polymerization protection lithium metal electrode 通用汽车环球科技运作有限责任公司 2024-05-24 CN claimed
US-11515538-B2 In-situ polymerization to protect lithium metal electrodes GM Global Technology Operations LLC (US) 2022-11-29 US claimed
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 EP claimed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US claimed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 EP claimed
JP-2008523165-A 2008-07-03 JP claimed
EP-1833880-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS Matsushita Electric Works, Ltd. (JP) 2007-09-19 EP claimed
WO-2006062219-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2006-06-15 WO claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US claimed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 US claimed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 US claimed
US-4466870-A REDUCTION OF ARYL HALIDES, CYCLOADDITION, PRODUCTION OF TETRAMESITYLDISILENE NORTH DAKOTA STATE UNIVERSITY DEVELOPMENT FOUNDATION (US) 1984-08-21 US claimed
CN-112652756-B In-situ polymerization protection lithium metal electrode 通用汽车环球科技运作有限责任公司 2024-05-24 CN disclosed
US-11515538-B2 In-situ polymerization to protect lithium metal electrodes GM Global Technology Operations LLC (US) 2022-11-29 US disclosed
US-20210111407-A1 IN-SITU POLYMERIZATION TO PROTECT LITHIUM METAL ELECTRODES GM Global Technology Operations LLC (US) 2021-04-15 US disclosed
EP-0571882-B1 Process for the preparation of polyolefin waxes HOECHST AG (DE) 1997-03-12 EP disclosed
EP-0571882-A2 Process for the preparation of polyolefin waxes HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-01 EP disclosed
US-4466870-A REDUCTION OF ARYL HALIDES, CYCLOADDITION, PRODUCTION OF TETRAMESITYLDISILENE NORTH DAKOTA STATE UNIVERSITY DEVELOPMENT FOUNDATION (US) 1984-08-21 US disclosed
US-4466870-A REDUCTION OF ARYL HALIDES, CYCLOADDITION, PRODUCTION OF TETRAMESITYLDISILENE NORTH DAKOTA STATE UNIVERSITY DEVELOPMENT FOUNDATION (US) 1984-08-21 US disclosed