SCHEMBL2974387

SCHEMBL2974387

O=P(O)(O)ON1CCOCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.45
MMP3 P08254 1/20 0.45
MMP8 P22894 1/20 0.45
ANPEP P15144 1/20 0.38
ALDH1A1 P00352 3/20 0.38
PDK1 Q15118 2/20 0.38
PDK2 Q15119 2/20 0.38
PDK3 Q15120 2/20 0.38
FAAH O00519 1/20 0.38
PHGDH O43175 1/20 0.38
ALDH2 P05091 1/20 0.38
MGLL Q99685 1/20 0.38
CA12 O43570 4/20 0.34
CA1 P00915 3/20 0.34
CA9 Q16790 3/20 0.34
CA2 P00918 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27758758 0.98 MMP1 (0.43) MMP1MMP3MMP8ANPEPALDH1A1
SCHEMBL329844 0.86 MMP1 (0.45) MMP1MMP3MMP8ANPEPCA12
SCHEMBL29071032 0.83 MMP1 (0.39) MMP1MMP3MMP8ANPEPL3MBTL1
SCHEMBL1615661 0.82 MMP1 (0.42) MMP1MMP3MMP8ANPEPCA12
SCHEMBL20473220 0.82 MMP1 (0.42) MMP1MMP3MMP8ANPEPCA12
SCHEMBL8763211 0.82
SCHEMBL7116797 0.81 MMP1 (0.35) MMP1MMP3MMP8ANPEPALDH1A1
SCHEMBL21145497 0.80 MMP1 (0.41) MMP1MMP3MMP8ANPEPCA12
SCHEMBL4302310 0.80 MMP1 (0.38) MMP1MMP3MMP8ANPEPALDH1A1
SCHEMBL20580622 0.80 MMP1 (0.37) MMP1MMP3MMP8ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118591391-A Muscle targeting complexes and their use for the treatment of myodystrophy 达因疗法公司 2024-09-03 CN claimed
CN-118510898-A Muscle targeting complexes and their use for the treatment of myodystrophy 达因疗法公司 2024-08-16 CN claimed
CN-118450896-A Muscle targeting complexes and their use for the treatment of myodystrophy 达因疗法公司 2024-08-06 CN claimed
CN-118401553-A Muscle targeting complexes and their use for the treatment of myodystrophy 达因疗法公司 2024-07-26 CN claimed
CN-118355035-A Muscle targeting complexes and their use for the treatment of myodystrophy 达因疗法公司 2024-07-16 CN claimed
CN-118207212-A Antisense nucleic acid 日本新药株式会社 2024-06-18 CN claimed
CN-118201640-A Muscle targeting complexes for the treatment of myodystrophy 达因疗法公司 2024-06-14 CN claimed
CN-117980006-A Muscle targeting complexes and formulations for the treatment of myodystrophy 达因疗法公司 2024-05-03 CN claimed
CN-117721110-A Antisense nucleic acid 日本新药株式会社 2024-03-19 CN claimed
CN-117202937-A Construction method and application of nucleic acid self-assembly mediated ADC (analog to digital converter) drug 安升(上海)医药科技有限公司 2023-12-08 CN claimed
CN-116368150-A Muscle targeting complexes and their use for the treatment of myodystrophy 达因疗法公司 2023-06-30 CN claimed
WO-2022206881-A1 METHOD FOR CONSTRUCTION OF NUCLEIC ACID SELF-ASSEMBLY-MEDIATED ADC DRUG AND USE THEREOF 安升(上海)医药科技有限公司 2022-10-06 WO claimed
EP-3822259-A1 METHOD FOR SYNTHESIZING VALSARTAN Zhejiang Huahai Pharmaceutical Co., Ltd. (CN) 2021-05-19 EP claimed
CN-111630167-A Antisense oligonucleotides for modulating T cell function 新加坡科技研究局 2020-09-04 CN claimed
CN-110114464-A Method by targeting the antisense strategy cancer of PRDM15 新加坡科技研究局 2019-08-09 CN claimed
CN-109490519-A A kind of leukocyte esterase Test paper and preparation method thereof 迪瑞医疗科技股份有限公司 2019-03-19 CN claimed
CN-105805426-B Pipeline runs through device 上海火克新材料有限公司 2017-10-27 CN claimed
EP-2077912-A1 FLUOROCARBON EMULSION STABILIZING SURFACTANTS The President and Fellows of Harvard College (US) 2009-07-15 EP claimed
CN-101213203-A Methods and compositions for regulating expression of nucleic acids at post-transcriptional level UNIV NORTH CAROLINA (US) 2008-07-02 CN claimed
WO-2008021123-A1 FLUOROCARBON EMULSION STABILIZING SURFACTANTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2008-02-21 WO claimed