Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 6/20 | 0.39 |
| ▸ | HTR2B | P41595 | 6/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16450616 | 0.79 | AGXT (0.62) | AGXTLOXL2CYP19A1ADRA2AHTR1A | |
| SCHEMBL24570862 | 0.79 | CA12 (0.43) | AGXTCA12CA1CA9 | |
| SCHEMBL1520921 | 0.76 | AGXT (1.00) | AGXTLOXL2CYP19A1ADRA2AHTR1A | |
| SCHEMBL14145540 | 0.76 | AGXT (0.68) | AGXTLOXL2CYP19A1HTR1AHTR2B | |
| SCHEMBL30514557 | 0.74 | HDAC6 (0.48) | CA12CA9SMN1; SMN2 | |
| SCHEMBL24570858 | 0.74 | HDAC6 (0.48) | CA12CA9SMN1; SMN2 | |
| SCHEMBL30688991 | 0.74 | DUT (0.34) | CA12CA1CA9 | |
| SCHEMBL31215584 | 0.74 | HDAC6 (0.33) | AGXTCA12CA1CA9 | |
| SCHEMBL19913913 | 0.74 | MEN1 (0.33) | AGXTESR1ESR2CA12CA1 | |
| SCHEMBL24087673 | 0.73 | AGXT (0.64) | AGXTLOXL2CYP19A1HTR1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022138812-A1 | TETRAHYDRO THIENOPYRIDINE SULFONAMIDE COMPOUND | モジュラス株式会社 | 2022-06-30 | — | — | WO | disclosed |