Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26613540 | 0.87 | NOTUM (0.39) | NOTUMMEN1KMT2AAVPR2 | |
| SCHEMBL29746333 | 0.87 | NOTUM (0.39) | NOTUMMEN1KMT2AAVPR2 | |
| SCHEMBL29746165 | 0.82 | SMN1; SMN2 (0.39) | NOTUMMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29746279 | 0.73 | NOTUM (0.42) | NOTUMMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30542595 | 0.71 | MEN1 (0.40) | MEN1KMT2AAVPR2 | |
| SCHEMBL26613459 | 0.71 | MEN1 (0.40) | MEN1KMT2AAVPR2 | |
| SCHEMBL28668775 | 0.71 | NOTUM (0.44) | NOTUMMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29746306 | 0.71 | SMN1; SMN2 (0.41) | NOTUMMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL26802173 | 0.68 | MEN1 (0.41) | NOTUMMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2255789 | 0.67 | PNMT (0.42) | MEN1KMT2AGAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022138888-A1 | TETRAHYDROQUINOLINE DERIVATIVE AND MEDICINAL USE THEREOF | 東レ株式会社 | 2022-06-30 | — | — | WO | disclosed |