Iothalamic Acid

Iothalamic Acid

SCHEMBL29746594

CNC(=O)c1c(I)c(NC(C)=O)c(I)c(C(=O)O)c1I

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.56
SMN1; SMN2 Q16637 1/20 0.51
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iothalamic Acid SCHEMBL38419 1.00 LMNA (0.56) LMNASMN1; SMN2TSHRMAPK1KDM4E
Iothalamic Acid SCHEMBL9563103 0.98 LMNA (0.55) LMNASMN1; SMN2TSHRMAPK1
SCHEMBL8752140 0.89 LMNA (0.67) LMNASMN1; SMN2TSHRMAPK1KDM4E
Hydrochloric Acid SCHEMBL8089018 0.87 LMNA (0.65) LMNASMN1; SMN2TSHRMAPK1KDM4E
Diatrizoic Acid SCHEMBL5960726 0.87 LMNA (0.65) LMNASMN1; SMN2TSHRMAPK1KDM4E
SCHEMBL21104711 0.87 LMNA (0.50) LMNASMN1; SMN2TSHRMAPK1
Diatrizoic Acid SCHEMBL8508 0.85 LMNA (0.67) LMNASMN1; SMN2TSHRMAPK1KDM4E
Diatrizoic Acid SCHEMBL7615048 0.85 LMNA (0.67) LMNASMN1; SMN2TSHRMAPK1KDM4E
SCHEMBL11292715 0.85 LMNA (0.36) LMNASMN1; SMN2TSHRMAPK1KDM4E
SCHEMBL9787545 0.85 LMNA (0.36) LMNASMN1; SMN2TSHRMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3741381-B1 A PEPTIDE FOR USE FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY UNIV CORNELL (US) 2024-04-24 EP claimed
US-20220403074-A1 ETHYLENE/1-HEXENE COPOLYMER HAVING IMPROVED FLEXIBILITY AND PROCESSIBILITY LG CHEM, LTD. (KR) 2022-12-22 US claimed
EP-3891207-B1 STEREOCOMPLEXES FOR THE DELIVERY OF ANTI-CANCER AGENTS TIEN DER YANG (US) 2022-11-02 EP claimed
US-12472301-B2 Negative pressure therapy system and methods 3IVE LABS, LLC (US) 2025-11-18 US disclosed
CN-118843428-A Sensing system and method for diagnosing kidney disease 德克斯康公司 2024-10-25 CN disclosed
US-12065558-B2 Mixed recycled polyolefin resin composition comprising recycled polyolefin resin recovered from waste separator and recycled product using the same SK INNOVATION CO., LTD. (KR) 2024-08-20 US disclosed
US-20240148913-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE,PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2024-05-09 US disclosed
CN-117858676-A Connector for optical coupling of multiplexers 博尔特医疗有限公司 2024-04-09 CN disclosed
WO-2024059244-A1 NEGATIVE PRESSURE THERAPY DEVICES, SYSTEMS, AND TREATMENT METHODS WITH INDWELLING URINARY CATHETERS 3IVE LABS, LLC (US) 2024-03-21 WO disclosed
US-20240091428-A1 Negative Pressure Therapy Devices, Systems, And Treatment Methods With Indwelling Urinary Catheters 3IVE LABS, LLC 2024-03-21 US disclosed
CN-117425446-A Active alignment system for laser optical coupling 博尔特医疗有限公司 2024-01-19 CN disclosed
CN-116583240-A Optical analyzer assembly with safety shut-off system for intravascular lithotripsy device 博尔特医疗有限公司 2023-08-11 CN disclosed
US-20230201165-A1 JAK INHIBITOR COMPOUND FOR TREATING SEVERE PNEUMONIA HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2023-06-29 US disclosed
US-20230068431-A1 Negative Pressure Therapy System and Methods 3IVE LABS, LLC 2023-03-02 US disclosed
US-20230060814-A1 Negative Pressure Therapy System and Methods 3IVE LABS, LLC 2023-03-02 US disclosed
WO-2023018924-A1 NEGATIVE PRESSURE THERAPY SYSTEM AND METHODS 3IVE LABS, LLC (US) 2023-02-16 WO disclosed
WO-2023018922-A1 NEGATIVE PRESSURE THERAPY SYSTEM AND METHODS 3IVE LABS, LLC (US) 2023-02-16 WO disclosed
CN-115666434-A Active alignment system for improving optical coupling of multiplexer of laser-driven intravascular lithotripsy device 博尔特医疗有限公司 2023-01-31 CN disclosed
CN-115334990-A Optical analyzer assembly and method for intravascular lithotripsy device 博尔特医疗有限公司 2022-11-11 CN disclosed
EP-4043519-A1 POLYETHYLENE COMPOSITION AND METHOD FOR PREPARING SAME LG Chem, Ltd. (KR) 2022-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230201165-A1 JAK INHIBITOR COMPOUND FOR TREATING SEVERE PNEUMONIA JAK1, JAK2, JAK3 LMNA 4633/4885SMN1; SMN2 3815/4885TSHR 2126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.