Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 15/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 12/20 | 0.48 |
| ▸ | CDK9 | P50750 | 12/20 | 0.48 |
| ▸ | CCNH | P51946 | 10/20 | 0.48 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.48 |
| ▸ | CCNK | O75909 | 7/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 7/20 | 0.47 |
| ▸ | CDK13 | Q14004 | 4/20 | 0.47 |
| ▸ | CDK2 | P24941 | 7/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22654520 | 1.00 | CDK7 (0.48) | CDK7CCNT1CDK9CCNHMNAT1 | |
| SCHEMBL20191043 | 1.00 | CDK7 (0.48) | CDK7CCNT1CDK9CCNHMNAT1 | |
| SCHEMBL20209310 | 0.91 | CDK7 (0.53) | CDK7CCNT1CDK9CCNHMNAT1 | |
| SCHEMBL20190962 | 0.91 | CDK7 (0.53) | CDK7CCNT1CDK9CCNHMNAT1 | |
| SCHEMBL20209562 | 0.90 | CDK7 (0.51) | CDK7CCNT1CDK9CCNHMNAT1 | |
| SCHEMBL20209673 | 0.89 | CDK7 (0.49) | CDK7CCNT1CDK9CCNHMNAT1 | |
| SCHEMBL17688386 | 0.88 | CDK7 (0.55) | CDK7CCNT1CDK9CCNHMNAT1 | |
| SCHEMBL18047281 | 0.87 | CDK7 (0.46) | CDK7CCNT1CDK9CCNHMNAT1 | |
| SCHEMBL16654840 | 0.86 | CDK7 (0.53) | CDK7CCNT1CDK9CCNHMNAT1 | |
| SCHEMBL16654926 | 0.85 | CDK7 (0.45) | CDK7CCNT1CDK9CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544971-B1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2022-07-06 | — | — | EP | disclosed |