Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 1/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 10/20 | 0.56 |
| ▸ | MET | P08581 | 3/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.49 |
| ▸ | CDK9 | P50750 | 2/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
| ▸ | INSR | P06213 | 3/20 | 0.48 |
| ▸ | IGF1R | P08069 | 2/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | CCNK | O75909 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CCND3 | P30281 | 1/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29747119 | 1.00 | ZAP70 (0.56) | ZAP70ALKMETPTK2MAPK9 | |
| SCHEMBL29747072 | 0.91 | EGFR (0.56) | ALKMETMAPK9MAPK10CDK9 | |
| SCHEMBL29747821 | 0.91 | EGFR (0.56) | ALKMETMAPK9MAPK10CDK9 | |
| SCHEMBL29747148 | 0.87 | ZAP70 (0.66) | ZAP70ALKINSRIGF1R | |
| SCHEMBL24429801 | 0.86 | EGFR (0.60) | ALKPTK2INSRIGF1R | |
| SCHEMBL22460093 | 0.86 | EGFR (0.60) | ALKPTK2INSRIGF1R | |
| SCHEMBL22460248 | 0.86 | EGFR (0.60) | ALKPTK2INSRIGF1R | |
| SCHEMBL24565202 | 0.83 | MAPK9 (0.47) | ALKMETPTK2MAPK9MAPK10 | |
| SCHEMBL29746846 | 0.80 | EGFR (0.52) | ALKMET | |
| SCHEMBL29747432 | 0.79 | ALK (0.55) | ALKMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | claimed |
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | disclosed |