SCHEMBL2974804

SCHEMBL2974804

CC(C)(O)C(=O)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12707421 0.84
SCHEMBL180091 0.78 TRPA1 (0.44)
SCHEMBL112282 0.78
SCHEMBL10804129 0.75
SCHEMBL2311220 0.75 TSHR (0.43)
SCHEMBL23643863 0.73
SCHEMBL10690402 0.73
SCHEMBL29131765 0.71
SCHEMBL3668666 0.71
Tert-Butanol SCHEMBL28190780 0.71 TSHR (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743078-A2 APOL1 INHIBITORS AND METHODS OF USE Maze Therapeutics, Inc. (US) 2026-05-20 EP disclosed
EP-4608830-A1 HETEROCYCLIC COMPOUNDS AS STING ANTAGONISTS Boehringer Ingelheim International GmbH (DE) 2025-09-03 EP disclosed
WO-2025015104-A2 APOL1 INHIBITORS AND METHODS OF USE MAZE THERAPEUTICS, INC. (US) 2025-01-16 WO disclosed
WO-2024089155-A1 HETEROCYCLIC COMPOUNDS AS STING ANTAGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-05-02 WO disclosed
WO-2024067820-A1 TRICYCLIC COMPOUNDS AS CDK INHIBITORS AND METHODS OF USING SAME SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) 2024-04-04 WO disclosed
CN-110156656-B Five-membered heteroaromatic ring derivative, preparation method thereof, pharmaceutical composition and application 上海迪诺医药科技有限公司 2023-04-07 CN disclosed
CN-110831942-B Fused indazolopyridinone compounds as antiviral agents 诺华股份有限公司 2023-04-04 CN disclosed
CN-114907340-A Fused azatricyclo derivatives, preparation method and application thereof in medicines 江苏恒瑞医药股份有限公司 2022-08-16 CN disclosed
EP-3998269-A1 FUSED INDAZOLE PYRIDONE COMPOUNDS AS ANTIVIRALS Novartis AG (CH) 2022-05-18 EP disclosed
EP-3615533-B1 FUSED INDAZOLE PYRIDONE COMPOUNDS AS ANTIVIRALS NOVARTIS AG (CH) 2021-09-08 EP disclosed
US-4855454-A CHEMICAL INTERMEDIATES; SWEETENERS PFIZER INC. (US) 1989-08-08 US disclosed
US-4804782-A ARTIFICIAL SWEETENER PFIZER, INC. (US) 1989-02-14 US disclosed
US-4517379-A ARTIFICIAL SWEETENER PFIZER INC. (US) 1985-05-14 US disclosed
EP-0069811-B1 BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF PFIZER INC. (US) 1984-10-24 EP disclosed
EP-0034876-B1 BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF PFIZER INC. (US) 1984-08-29 EP disclosed
US-4454328-A SWEETENERS PFIZER INC. (US) 1984-06-12 US disclosed
US-4411925-A STABLE SWEETENERS PFIZER INC. (US) 1983-10-25 US disclosed
US-4399163-A ARTIFICIAL SWEETENERS PFIZER INC. (US) 1983-08-16 US disclosed
EP-0069811-A1 Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof PFIZER INC. (US) 1983-01-19 EP disclosed
EP-0034876-A2 Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof PFIZER INC. (US) 1981-09-02 EP disclosed