SCHEMBL29750302

SCHEMBL29750302

C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(=N)N)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ NRP1 O14786 3/20 0.44
▸ XIAP P98170 1/20 0.44
▸ NTSR2 O95665 4/20 0.41
▸ NTSR1 P30989 4/20 0.41
▸ SORT1 Q99523 4/20 0.41
▸ F2 P00734 2/20 0.40
▸ OPRM1 P35372 3/20 0.40
▸ DPP4 P27487 1/20 0.39
▸ FAP Q12884 1/20 0.39
▸ DPP8 Q6V1X1 1/20 0.39
▸ DPP9 Q86TI2 1/20 0.39
▸ DPP7 Q9UHL4 1/20 0.39
▸ GRB2 P62993 1/20 0.38
▸ OPRK1 P41145 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31748448 0.90 NTSR2 (0.48) NTSR2NTSR1SORT1OPRM1OPRK1
SCHEMBL31427004 0.90 NRP1 (0.44) NRP1XIAPNTSR2NTSR1SORT1
SCHEMBL30658565 0.89 XIAP (0.48) NRP1XIAPNTSR2NTSR1SORT1
SCHEMBL22872708 0.89 NRP1 (0.54) NRP1NTSR2NTSR1SORT1F2
SCHEMBL30415970 0.89 NRP1 (0.51) NRP1NTSR2NTSR1SORT1OPRM1
SCHEMBL29853254 0.89 NRP1 (0.47) NRP1XIAPNTSR2NTSR1SORT1
SCHEMBL31487190 0.89 NRP1 (0.47) NRP1XIAPNTSR2NTSR1SORT1
SCHEMBL30974453 0.89 ACE (0.40) NRP1XIAPF2GRB2
SCHEMBL29788329 0.88 NTSR2 (0.51) NTSR2NTSR1SORT1
SCHEMBL31303183 0.88 NRP1 (0.52) NRP1XIAPNTSR2NTSR1SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306534-A1 MULTIFUNCTIONAL POLYPEPTIDE AND APPLICATION THEREOF IN FIELD OF MEDICINES Wuhan Innerse Pharmaceutical Inc. (CN) 2024-01-17 — — EP claimed
WO-2022188878-A1 MULTIFUNCTIONAL POLYPEPTIDE AND APPLICATION THEREOF IN FIELD OF MEDICINES 武汉英纳氏药业有限公司 2022-09-15 — — WO claimed
WO-2022156190-A1 ANTIHYPERTENSIVE PEPTIDE, LONG-ACTING ANTIHYPERTENSIVE PEPTIDE, AND PREPARATION METHODS THEREFOR 南方海洋科学与工程广东省实验室(湛江) 2022-07-28 — — WO claimed
EP-4337965-A1 CLOTTABILITY-BASED PERSONALIZED TREATMENT (CPT) SYSTEM Pun, San (CH) 2024-03-20 — — EP disclosed
EP-4306534-A1 MULTIFUNCTIONAL POLYPEPTIDE AND APPLICATION THEREOF IN FIELD OF MEDICINES Wuhan Innerse Pharmaceutical Inc. (CN) 2024-01-17 — — EP disclosed
WO-2023275213-A1 CLOTTABILITY-BASED PERSONALIZED TREATMENT (CPT) SYSTEM PUN SAN (CH) 2023-01-05 — — WO disclosed
CN-112661811-B Antihypertensive peptide, long-acting antihypertensive peptide and preparation method thereof 南方海洋科学与工程广东省实验室(湛江) 2022-10-21 — — CN disclosed
WO-2022188878-A1 MULTIFUNCTIONAL POLYPEPTIDE AND APPLICATION THEREOF IN FIELD OF MEDICINES 武汉英纳氏药业有限公司 2022-09-15 — — WO disclosed
WO-2022156190-A1 ANTIHYPERTENSIVE PEPTIDE, LONG-ACTING ANTIHYPERTENSIVE PEPTIDE, AND PREPARATION METHODS THEREFOR 南方海洋科学与工程广东省实验室(湛江) 2022-07-28 — — WO disclosed
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