SCHEMBL29754178

SCHEMBL29754178

Cc1c2ccccc2c(OCc2ccccc2)c2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.55
MAPT P10636 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
MAPK1 P28482 1/20 0.55
LMNA P02545 3/20 0.47
GAA P10253 2/20 0.47
POLB P06746 1/20 0.47
ALDH1A1 P00352 3/20 0.47
TSHR P16473 3/20 0.47
USP2 O75604 1/20 0.47
HSD17B10 Q99714 1/20 0.47
PTPN1 P18031 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.44
HPGD P15428 2/20 0.44
MEN1 O00255 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2C19 P33261 2/20 0.42
CYP1A2 P05177 1/20 0.42
PTGS1 P23219 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL755335 1.00 L3MBTL1 (0.55) L3MBTL1MAPTTDP1MAPK1LMNA
SCHEMBL756581 0.89 TSHR (0.52) L3MBTL1MAPTTDP1MAPK1LMNA
SCHEMBL29366230 0.89 TSHR (0.52) L3MBTL1MAPTTDP1MAPK1LMNA
SCHEMBL29367369 0.85 L3MBTL1 (0.47) L3MBTL1MAPTTDP1MAPK1LMNA
SCHEMBL754080 0.85 L3MBTL1 (0.47) L3MBTL1MAPTTDP1MAPK1LMNA
SCHEMBL24968079 0.83 L3MBTL1 (0.63) L3MBTL1MAPTTDP1MAPK1LMNA
SCHEMBL1127799 0.83 TSHR (0.50) L3MBTL1MAPTTDP1MAPK1LMNA
SCHEMBL29366541 0.83 TSHR (0.50) L3MBTL1MAPTTDP1MAPK1LMNA
SCHEMBL14655869 0.81 MAPT (0.39) L3MBTL1MAPTTDP1MAPK1LMNA
SCHEMBL30463386 0.77 IDO1 (0.56) MAPTTDP1LMNAMAOBACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4481059-A2 MOLECULAR ARRAY GENERATION USING PHOTORESIST 10x Genomics, Inc. (US) 2024-12-25 EP disclosed
WO-2024006799-A1 COVALENT ATTACHMENT OF SPLINT OLIGONUCLEOTIDES FOR MOLECULAR ARRAY GENERATION USING LIGATION 10X GENOMICS, INC. (US) 2024-01-04 WO disclosed
EP-4271511-A1 MOLECULAR ARRAY GENERATION USING PHOTORESIST 10X Genomics, Inc. (US) 2023-11-08 EP disclosed
WO-2022147140-A1 MOLECULAR ARRAY GENERATION USING PHOTORESIST 10X GENOMICS, INC. (US) 2022-07-07 WO disclosed