Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22546088 | 1.00 | HSD17B10 (0.49) | HSD17B10KDM4ETP53TSHRRPS6KA3 | |
| SCHEMBL7269557 | 0.80 | RPS6KA3 (0.52) | HSD17B10TSHRRPS6KA3CYP1A2CYP2C9 | |
| SCHEMBL2490332 | 0.78 | GRM2 (0.52) | HSD17B10KDM4ERPS6KA3CYP1A2CYP2C9 | |
| SCHEMBL1890494 | 0.77 | RPS6KA3 (0.45) | HSD17B10RPS6KA3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2491842 | 0.73 | GAA (0.63) | HSD17B10TP53RPS6KA3CYP1A2CYP2C9 | |
| SCHEMBL9618157 | 0.72 | RPS6KA3 (0.84) | TSHRRPS6KA3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2490331 | 0.72 | RPS6KA3 (0.60) | RPS6KA3CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL2488627 | 0.72 | CYP1A2 (0.59) | RPS6KA3CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL27873758 | 0.72 | RPS6KA3 (0.64) | KDM4ERPS6KA3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3403852 | 0.71 | SLC9A1 (0.63) | TSHRRPS6KA3CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118702683-A | Phenyl ethers and anilines of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-113993861-B | Phenyl ethers and anilines of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20220259182-A1 | BENZETHERS AND ANILINES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2022-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220259182-A1 | BENZETHERS AND ANILINES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | JAK3, JAK1, JAK2 | HSD17B10 2161/4885KDM4E 553/4885TP53 972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.