Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.46 |
| ▸ | RXRB | P28702 | 5/20 | 0.46 |
| ▸ | RXRG | P48443 | 5/20 | 0.46 |
| ▸ | POLQ | O75417 | 8/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20563511 | 1.00 | RXRA (0.46) | RXRARXRBRXRGPOLQPTGDR2 | |
| SCHEMBL6717126 | 0.85 | KDM1A (0.41) | RXRARXRBRXRGPOLQKDM1A | |
| SCHEMBL22235493 | 0.85 | POLQ (0.42) | RXRARXRBRXRGPOLQPTGDR2 | |
| SCHEMBL15532197 | 0.83 | FFAR4 (0.45) | RXRARXRBRXRGPTGDR2 | |
| SCHEMBL20562983 | 0.81 | NOTUM (0.43) | POLQPTGDR2 | |
| SCHEMBL30716953 | 0.81 | POLQ (0.61) | RXRARXRBRXRGPOLQPTGDR2 | |
| SCHEMBL3741058 | 0.81 | POLQ (0.61) | RXRARXRBRXRGPOLQPTGDR2 | |
| SCHEMBL892786 | 0.81 | IDO1 (0.53) | RXRARXRBRXRGPOLQPTGDR2 | |
| SCHEMBL14793818 | 0.81 | CAMK2A (0.47) | RXRARXRBRXRGPOLQPTGS2 | |
| SCHEMBL29009933 | 0.80 | PTGDR2 (0.37) | RXRARXRBRXRGPOLQPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436955-B | Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof | 复旦大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-111032647-B | Lysophosphatidic acid receptor 1 (LPAR 1) inhibitor compounds | 伊莱利利公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-114436955-A | Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof | 复旦大学 | 2022-05-06 | — | — | CN | disclosed |