SCHEMBL29754258

SCHEMBL29754258

O=c1c2ccccc2[nH]c2cc3ccccc3n12

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.77
NTRK1 P04629 1/20 0.49
MAPK8 P45983 1/20 0.49
MAPK9 P45984 1/20 0.49
MAPK10 P53779 1/20 0.49
NTRK3 Q16288 1/20 0.49
NTRK2 Q16620 1/20 0.49
NPEPPS P55786 1/20 0.48
ALDH1A1 P00352 6/20 0.44
ADORA3 P0DMS8 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA2B P29275 1/20 0.44
ADORA1 P30542 1/20 0.44
CA12 O43570 1/20 0.44
RNASEH1 O60930 1/20 0.44
ERCC1 P07992 1/20 0.44
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44
CA9 Q16790 1/20 0.44
ERCC4 Q92889 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31594185 0.80 CDC25B (0.54) CDC25BNTRK1MAPK8MAPK9MAPK10
SCHEMBL20779950 0.79 CDC25B (0.65) CDC25BALDH1A1KDM4EKMT2ANPC1
SCHEMBL30203958 0.79 CDC25B (0.65) CDC25BALDH1A1KDM4EKMT2ANPC1
SCHEMBL26826893 0.77 CDC25B (0.72) CDC25BNTRK1MAPK8MAPK9MAPK10
SCHEMBL14336308 0.77 NPEPPS (0.50) CDC25BNPEPPSALDH1A1ADORA3ADORA2A
SCHEMBL22045317 0.77 CDC25B (0.54) CDC25BKDM4EGAACASP7CYP1A2
SCHEMBL12324447 0.74 GAA (0.51) CDC25BNTRK1MAPK8MAPK9MAPK10
SCHEMBL9880250 0.73 CDC25B (0.50) CDC25BALDH1A1ADORA3KDM4EKMT2A
SCHEMBL11572361 0.73 HSD17B10 (0.49) CDC25BALDH1A1CA12CA9KDM4E
SCHEMBL29412453 0.73 HSD17B10 (0.49) CDC25BALDH1A1CA12CA9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112667922-B Novel coronavirus traditional Chinese medicine formula recommendation method and system based on collaborative filtering 山东大学 2022-06-28 CN disclosed