Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28499518 | 0.88 | KMT2A (0.50) | SMN1; SMN2POLBKDM4EGAANPC1 | |
| SCHEMBL29754948 | 0.78 | TP53 (0.54) | SMN1; SMN2POLBLMNAKDM4EGAA | |
| SCHEMBL29754800 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBLMNAKDM4EGAA | |
| SCHEMBL29754788 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBLMNAKDM4EGAA | |
| Bromide SCHEMBL3845346 | 0.73 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBKDM4EGAARAB9A | |
| SCHEMBL2129381 | 0.72 | SMN1; SMN2 (0.66) | SMN1; SMN2POLBLMNAKDM4EGAA | |
| SCHEMBL29755000 | 0.72 | GAA (0.55) | SMN1; SMN2POLBLMNATSHRGAA | |
| SCHEMBL3633228 | 0.71 | SMN1; SMN2 (0.64) | SMN1; SMN2POLBKDM4ETSHRGAA | |
| Bromide SCHEMBL3845341 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAKDM4ETSHRGAA | |
| SCHEMBL2127575 | 0.70 | SMN1; SMN2 (1.00) | SMN1; SMN2POLBLMNAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028833-B | Para-aminosalicylic acid azole derivative and preparation method and application thereof | 西南大学 | 2022-07-05 | — | — | CN | disclosed |