Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL3629891 | 0.88 | GAA (0.58) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2129381 | 0.87 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL23906981 | 0.84 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5497587 | 0.82 | CYP1A1 (0.57) | ALDH1A1KDM4ECYP1A1KMT2ACA12 | |
| SCHEMBL7858895 | 0.80 | PTPRC (0.58) | SMN1; SMN2ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL13593266 | 0.80 | KMT2A (0.61) | ALDH1A1KDM4ECYP1A1KMT2ACA12 | |
| SCHEMBL11892329 | 0.80 | EGFR (0.56) | SMN1; SMN2HSD17B10KMT2ACA12CA1 | |
| SCHEMBL23309774 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL2127575 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL613429 | 0.79 | SMN1; SMN2 (0.76) | SMN1; SMN2KDM4EHPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9149530-B2 | Compositions and methods for enhancing active agent absorption | NEXUS PHARMA, INC. (US) | 2015-10-06 | — | — | US | disclosed |
| US-8426466-B2 | Compositions and methods for enhancing active agent absorption | NEXUS PHARMA, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| EP-2150243-A2 | COMPOSITIONS AND METHODS FOR ENHANCING ACTIVE AGENT ABSORPTION | Nexus Pharma, Inc. (US) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008144690-A2 | COMPOSITIONS AND METHODS FOR ENHANCING ACTIVE AGENT ABSORPTION | NEXUS PHARMA, INC. (US) | 2008-11-27 | — | — | WO | disclosed |
| US-20070269500-A1 | Compositions and methods for enhancing active agent absorption | NEXUS PHARMA, INC. | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070269500-A1 | Compositions and methods for enhancing active agent absorption | FABP2, SLC10A2, SI | SMN1; SMN2 1589/4885ALDH1A1 1881/4885KDM4E 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.