Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29755407 | 0.86 | SOS1 (0.48) | SOS1KRAS | |
| SCHEMBL23326450 | 0.83 | SOS1 (0.69) | SOS1KRAS | |
| SCHEMBL23326449 | 0.83 | SOS1 (0.69) | SOS1KRAS | |
| SCHEMBL29755261 | 0.82 | SOS1 (0.57) | SOS1KRAS | |
| SCHEMBL29755233 | 0.82 | SOS1 (0.55) | SOS1KRAS | |
| SCHEMBL29755485 | 0.82 | SOS1 (0.57) | SOS1KRAS | |
| SCHEMBL29755172 | 0.79 | SOS1 (0.60) | SOS1KRAS | |
| SCHEMBL29755536 | 0.79 | SOS1 (0.57) | SOS1KRAS | |
| SCHEMBL24671984 | 0.79 | SOS1 (0.66) | SOS1KRAS | |
| SCHEMBL29755308 | 0.78 | SOS1 (0.56) | SOS1KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022156792-A1 | HETEROCYCLIC COMPOUNDS AS SOS1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-07-28 | — | — | WO | disclosed |