Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29755218 | 0.91 | SOS1 (0.50) | SOS1KRAS | |
| SCHEMBL29755425 | 0.89 | SOS1 (0.49) | SOS1KRAS | |
| SCHEMBL29755282 | 0.86 | SOS1 (0.63) | SOS1KRAS | |
| SCHEMBL29755249 | 0.84 | SOS1 (0.48) | SOS1KRAS | |
| SCHEMBL29755534 | 0.80 | SOS1 (0.45) | SOS1KRAS | |
| SCHEMBL29849038 | 0.76 | SOS1 (0.61) | SOS1KRAS | |
| SCHEMBL29824204 | 0.74 | SOS1 (0.45) | SOS1KRAS | |
| SCHEMBL30014869 | 0.74 | SOS1 (0.70) | SOS1KRAS | |
| SCHEMBL23520558 | 0.74 | SOS1 (0.49) | SOS1KRAS | |
| SCHEMBL23521100 | 0.73 | SOS1 (0.57) | SOS1KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022156792-A1 | HETEROCYCLIC COMPOUNDS AS SOS1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-07-28 | — | — | WO | disclosed |