SCHEMBL29755484

SCHEMBL29755484

CC(C)(C)OC(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 8/20 0.55
▸ ACE P12821 1/20 0.48
▸ MDM2 Q00987 1/20 0.48
▸ MDM4 O15151 2/20 0.47
▸ TP53 P04637 2/20 0.47
▸ TNF P01375 1/20 0.46
▸ TLR2 O60603 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17697136 0.94 MDM2 (0.53) PTPN1MDM2MDM4TP53TLR2
SCHEMBL30523139 0.94 MDM2 (0.53) PTPN1MDM2MDM4TP53TLR2
SCHEMBL23728660 0.94 MDM2 (0.53) PTPN1MDM2MDM4TP53TLR2
SCHEMBL23728661 0.94 MDM2 (0.53) PTPN1MDM2MDM4TP53TLR2
SCHEMBL29105490 0.91 PTPN1 (0.49) PTPN1ACEMDM2MDM4TP53
SCHEMBL29105492 0.91 PTPN1 (0.49) PTPN1ACEMDM2MDM4TP53
SCHEMBL12658044 0.91 PTPN1 (0.53) PTPN1MDM2MDM4TP53TLR2
SCHEMBL30523140 0.91 PTPN1 (0.53) PTPN1MDM2MDM4TP53TLR2
SCHEMBL7902079 0.91 PTPN1 (0.51) PTPN1ACEMDM2MDM4TP53
SCHEMBL22373690 0.90 MDM2 (0.54) PTPN1MDM2MDM4TP53TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12433936-B2 High-purity adrenocorticotropic hormone analogue and a large-scale preparation method thereof Nanjing Hanxin Pharmaceutical Technology Co., Ltd. (CN) 2025-10-07 — — US disclosed
EP-4602064-A1 METHOD OF MANUFACTURING A PEPTIDE WITH A LYSINE DERIVATIVE Bachem Holding AG (CH) 2025-08-20 — — EP disclosed
WO-2024079043-A1 METHOD OF MANUFACTURING A PEPTIDE WITH A LYSINE DERIVATIVE BACHEM HOLDING AG (CH) 2024-04-18 — — WO disclosed
US-20220401521-A1 A HIGH-PURITY ADRENOCORTICOTROPIC HORMONE ANALOGUE AND A LARGE-SCALE PREPARATION METHOD THEREOF Nanjing Hanxin Pharmaceutical Technology Co., Ltd. (CN) 2022-12-22 — — US disclosed
WO-2022217395-A1 HIGH-PURITY HUMAN CORTICOTROPIN OR ANALOG THEREOF, AND LARGE-SCALE PREPARATION METHOD THEREFOR 南京汉欣医药科技有限公司 2022-10-20 — — WO disclosed
US-11419919-B1 High-purity adrenocorticotropic hormone, analogue and a large-scale preparation method thereof Nanjing Hanxin Pharmaceutical Technology Co., Ltd. (CN) 2022-08-23 — — US disclosed
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