Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261546 | 0.94 | PTPN1 (0.49) | PTPN1MDM2GRB2MDM4TP53 | |
| SCHEMBL29755484 | 0.91 | PTPN1 (0.55) | PTPN1MDM2MDM4TP53TLR2 | |
| SCHEMBL23728661 | 0.88 | MDM2 (0.53) | PTPN1MDM2MDM4TP53TLR2 | |
| SCHEMBL30523139 | 0.88 | MDM2 (0.53) | PTPN1MDM2MDM4TP53TLR2 | |
| SCHEMBL23728660 | 0.88 | MDM2 (0.53) | PTPN1MDM2MDM4TP53TLR2 | |
| SCHEMBL17697136 | 0.88 | MDM2 (0.53) | PTPN1MDM2MDM4TP53TLR2 | |
| SCHEMBL120691 | 0.86 | MDM4 (0.52) | PTPN1MDM2MDM4TP53SLC17A5 | |
| SCHEMBL29401272 | 0.86 | MDM4 (0.52) | PTPN1MDM2MDM4TP53SLC17A5 | |
| SCHEMBL12658044 | 0.86 | PTPN1 (0.53) | PTPN1MDM2MDM4TP53TLR2 | |
| SCHEMBL30523140 | 0.86 | PTPN1 (0.53) | PTPN1MDM2MDM4TP53TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319702-B1 | NUCLEOTIDE SEQUENCS CODING AN ENZYMATIC POLYPEPTIDE AND CELL TARGETING COMPOUND; FOR USE IN TREATMENT OF CANCER | GLAXO WELLCOME, INC. | 2001-11-20 | — | — | US | disclosed |
| US-6140100-A | CONJUGATE POLYPEPTIDE WHICH IS TISSUE PREFERENTIAL; ANTICARCINOGENIC AGENTS | GLAXO WELLCOME INC. (US) | 2000-10-31 | — | — | US | disclosed |