Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122709 | 1.00 | L3MBTL1 (0.40) | L3MBTL1DYRK1BKDM5BCREBBPABL1 | |
| SCHEMBL20122925 | 0.92 | DYRK1B (0.46) | L3MBTL1DYRK1BCREBBPDYRK1AALK | |
| SCHEMBL30664251 | 0.92 | DYRK1B (0.46) | L3MBTL1DYRK1BCREBBPDYRK1AALK | |
| SCHEMBL29756420 | 0.89 | L3MBTL1 (0.42) | L3MBTL1KDM5BCREBBPABL1BCR | |
| SCHEMBL20122987 | 0.89 | L3MBTL1 (0.42) | L3MBTL1KDM5BCREBBPABL1BCR | |
| SCHEMBL30664263 | 0.85 | CREBBP (0.42) | DYRK1BKDM5BCREBBPDYRK1AGABRA1 | |
| SCHEMBL20122909 | 0.85 | CREBBP (0.42) | DYRK1BKDM5BCREBBPDYRK1AGABRA1 | |
| SCHEMBL20122973 | 0.81 | CREBBP (0.43) | L3MBTL1CREBBPDYRK1AALK | |
| SCHEMBL30664313 | 0.81 | CREBBP (0.43) | L3MBTL1CREBBPDYRK1AALK | |
| SCHEMBL20122718 | 0.81 | BRD4 (0.34) | DYRK1BCREBBPDYRK1APKMBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382496-B | Substituted pyrido [3,4-b ] indoles for the treatment of cartilage disorders | 赛诺菲 | 2022-08-09 | — | — | CN | claimed |
| CN-110382496-B | Substituted pyrido [3,4-b ] indoles for the treatment of cartilage disorders | 赛诺菲 | 2022-08-09 | — | — | CN | disclosed |