⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30352405 | 0.94 | MEN1 (0.31) | — | |
| SCHEMBL7478639 | 0.81 | — | — | |
| SCHEMBL1667058 | 0.67 | — | — | |
| SCHEMBL15716188 | 0.67 | — | — | |
| SCHEMBL1012395 | 0.66 | — | — | |
| SCHEMBL28856862 | 0.65 | — | — | |
| SCHEMBL28263515 | 0.65 | — | — | |
| SCHEMBL366939 | 0.64 | LMNA (0.36) | — | |
| SCHEMBL28985438 | 0.64 | MEN1 (0.35) | — | |
| SCHEMBL29065118 | 0.64 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728168-B | Triazole carbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117295724-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-115942972-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115867556-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-114728168-A | Triazolecarbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2022-07-08 | — | — | CN | disclosed |