Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 6/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | CKS1B | P61024 | 2/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22275780 | 1.00 | GLO1 (0.57) | GLO1ALOX15HTTPTGS1CKS1B | |
| SCHEMBL24461367 | 0.85 | GLO1 (0.55) | GLO1ALOX15HTTPTGS1CKS1B | |
| SCHEMBL25996431 | 0.83 | CKS1B (0.48) | GLO1ALOX15HTTPTGS1CKS1B | |
| SCHEMBL4074257 | 0.78 | GLO1 (0.64) | GLO1ALOX15HTTPTGS1CKS1B | |
| SCHEMBL27863537 | 0.77 | GLO1 (0.62) | GLO1ALOX15HTTPTGS1CKS1B | |
| SCHEMBL30855343 | 0.76 | GRM5 (0.41) | HTTATRL3MBTL1 | |
| SCHEMBL11489377 | 0.76 | RRM2 (0.37) | ATRL3MBTL1HSD17B10 | |
| SCHEMBL20371667 | 0.75 | IKBKB (0.48) | GLO1HTTCKS1BSKP2KEAP1 | |
| SCHEMBL29897528 | 0.75 | GLO1 (0.49) | GLO1ALOX15HTTCKS1BSKP2 | |
| SCHEMBL20701453 | 0.75 | GLO1 (0.49) | GLO1ALOX15HTTCKS1BSKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728168-B | Triazole carbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-114728168-A | Triazolecarbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2022-07-08 | — | — | CN | disclosed |