Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971916 | 1.00 | MAPK1 (0.40) | MAPK1PTK2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL24405763 | 0.82 | SMN1; SMN2 (0.52) | MAPK1PTK2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28007123 | 0.82 | KDR (0.50) | MAPK1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL915781 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDKDM4EHCAR2HSD17B10 | |
| SCHEMBL29378297 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDKDM4EHCAR2HSD17B10 | |
| SCHEMBL1160933 | 0.81 | HCAR2 (0.36) | PTK2SMN1; SMN2HPGDCRHR1KDR | |
| SCHEMBL29608609 | 0.81 | HCAR2 (0.36) | PTK2SMN1; SMN2HPGDCRHR1KDR | |
| SCHEMBL31382687 | 0.80 | SCN9A (0.39) | MAPK1PTK2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL18124622 | 0.80 | KDR (0.49) | MAPK1PTK2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4869343 | 0.80 | SCN9A (0.39) | MAPK1PTK2SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728168-B | Triazole carbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-4058144-A1 | TRIAZOLE CARBAMATE PYRIDYL SULFONAMIDES AS LPA RECEPTOR ANTAGONISTS AND USES THEREOF | Gilead Sciences, Inc. (US) | 2022-09-21 | — | — | EP | disclosed |
| CN-114728168-A | Triazolecarbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2022-07-08 | — | — | CN | disclosed |