SCHEMBL2975869

SCHEMBL2975869

C=CC(=O)Oc1ccc(F)cc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.55
TGM2 P21980 1/20 0.47
KMT2A Q03164 3/20 0.45
ATM Q13315 1/20 0.42
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
THRA P10827 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.38
HPGD P15428 1/20 0.38
FAAH O00519 1/20 0.38
HSD11B1 P28845 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31302864 0.91 KMT2A (0.50) THRBTGM2KMT2AATMCES2
SCHEMBL2587522 0.89 THRB (0.64) THRBTGM2KMT2AKDM4EMEN1
SCHEMBL12086452 0.86 KMT2A (0.47) THRBKMT2AMEN1GAASMN1; SMN2
SCHEMBL15397357 0.82 TTR (0.47) THRBKMT2AATMKDM4EMEN1
SCHEMBL14173219 0.82 THRB (0.58) THRBTGM2KMT2AMEN1GAA
SCHEMBL31379798 0.82 THRB (0.58) THRBTGM2KMT2AKDM4EMEN1
SCHEMBL2583822 0.82 THRB (0.58) THRBTGM2KMT2AMEN1GAA
SCHEMBL15695636 0.82 THRB (0.58) THRBTGM2KMT2AKDM4EMEN1
SCHEMBL802752 0.82 THRB (0.58) THRBTGM2KMT2AKDM4EMEN1
SCHEMBL28894377 0.82 KMT2A (0.48) KMT2AATMCES2CES1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109796561-B Aromatic ring polycarboxylic acid water reducing agent mother liquor and preparation method and application thereof 科之杰新材料集团(贵州)有限公司 2021-06-15 CN claimed
CN-109796561-A A kind of aromatic ring class polycarboxylate superplasticizer mother liquor and its preparation method and application 贵州科之杰新材料有限公司 2019-05-24 CN claimed
US-20140242722-A1 ARTICLE AND METHOD FOR DETECTION OF A DRUG IN A LIQUID MEDIUM MEDTECH DETECT, LLC (US) 2014-08-28 US claimed
WO-2014062910-A1 SPIROPYRAN-BASED COLORIMETRIC DETECTION MEDTECH DETECT, LLC (US) 2014-04-24 WO claimed
US-7446135-B2 Block copolymeric dispersant for pigment particle in aqueous system, and ink composition comprising the same SAMSUNG ELECTRONCIS CO., LTD. (KR) 2008-11-04 US claimed
US-20050132931-A1 Block copolymeric dispersant for pigment particle in aqueous system, and ink composition comprising the same SAMSUNG ELECTRONICS CO., LTD. 2005-06-23 US claimed
US-4801669-A Process for the quasi-ionic polymerization of acrylic acid derivatives BAYER AKTIENGESELLSCHAFT (DE) 1989-01-31 US claimed
EP-0095932-B1 THE USE OF A PARTICULATE POLYMER AS A CARRIER FOR BIOLOGICAL SUBSTANCES AND THE LIKE AND SUCH SUBSTANCES SUPPORTED ON THE CARRIER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-08-06 EP claimed
EP-0095932-A1 The use of a particulate polymer as a carrier for biological substances and the like and such substances supported on the carrier JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-12-07 EP claimed
CN-109796561-B Aromatic ring polycarboxylic acid water reducing agent mother liquor and preparation method and application thereof 科之杰新材料集团(贵州)有限公司 2021-06-15 CN disclosed
US-10829466-B2 Stilbene derivative and preparation method thereof BEIJING INSTITUTE OF TECHNOLOGY (CN) 2020-11-10 US disclosed
US-10676554-B2 Polymer compound, film obtained by hardening this polymer compound and electronic device comprising this film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-06-09 US disclosed
US-20200148662-A1 NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF BEIJING INSTITUTE OF TECHNOLOGY (CN) 2020-05-14 US disclosed
US-20190250509-A1 PHOTOSENSITIVE COMPOSITION AND ORGANIC THIN-FILM TRANSISTOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-08-15 US disclosed
EP-0141610-A2 Optical elements comprising polymers of (meth)acrylate esters Hitachi Chemical Co., Ltd. (JP) 1985-05-15 EP disclosed
US-4508880-A ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANOSILICON, (-TIN, OR-GERMANIUM) INITIATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-02 US disclosed
EP-0095932-A1 The use of a particulate polymer as a carrier for biological substances and the like and such substances supported on the carrier JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-12-07 EP disclosed
US-4417034-A POLYMERIZING ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANO-SILICON, -TIN, OR-GERMANIUM INITIATORS E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-22 US disclosed
US-4414372-A ADDITION POLYMERS WITH FUNCTIONAL END GROUPS E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-08 US disclosed
EP-0068887-A1 \"Living\" polymers and process for their preparation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10829466-B2 Stilbene derivative and preparation method thereof STS, F12, GLB1 THRB 779/4885TGM2 1754/4885KMT2A 3011/4885
US-20200148662-A1 NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF STS, F12, STK38L THRB 868/4885TGM2 2168/4885KMT2A 3156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.