Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24526523 | 1.00 | PRMT5 (0.43) | PRMT5BLMKDM4EALOX15CHRNB2 | |
| SCHEMBL24526663 | 0.82 | GRIN3B (0.35) | GRIN3BGRIN1GRIN2C | |
| SCHEMBL24526986 | 0.79 | CHRNB2 (0.47) | BLMKDM4EALOX15CHRNB2CHRNB4 | |
| SCHEMBL24526984 | 0.78 | GRIN1 (0.34) | GRIN3BGRIN1GRIN2C | |
| SCHEMBL24527002 | 0.78 | GRIN1 (0.32) | GRIN3BGRIN1GRIN2C | |
| SCHEMBL24526649 | 0.78 | GRIN1 (0.36) | GRIN3BGRIN1GRIN2C | |
| SCHEMBL29759163 | 0.78 | GRIN1 (0.36) | GRIN3BGRIN1GRIN2C | |
| SCHEMBL24526648 | 0.78 | GRIN1 (0.36) | GRIN3BGRIN1GRIN2C | |
| SCHEMBL24526525 | 0.78 | GRIN3B (0.33) | GRIN3BGRIN1GRIN2C | |
| SCHEMBL24526983 | 0.78 | GRIN1 (0.33) | GRIN3BGRIN1GRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129047-A2 | NOVEL MODULATORS OF THE NMDA RECEPTOR | H. LUNDBECK A/S (DK) | 2022-06-23 | — | — | WO | disclosed |