Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 7/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KYNU | Q16719 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29759255 | 0.95 | PTGER1 (0.42) | PTGER1MAPTLMNAMEN1KMT2A | |
| SCHEMBL29759249 | 0.90 | PTGER1 (0.46) | PTGER1MAPTLMNAAAK1CYP3A4 | |
| SCHEMBL29759264 | 0.87 | ITGB3 (0.41) | PTGER1ITGAVITGB3ITGA2BEGLN2 | |
| SCHEMBL29759284 | 0.82 | PTGER1 (0.41) | PTGER1MAPTLMNACYP3A4ALDH1A1 | |
| SCHEMBL29759270 | 0.81 | ITGB3 (0.37) | PTGER1ITGAVITGB3ITGA2BEGLN2 | |
| SCHEMBL24526778 | 0.79 | CTSA (0.44) | KCNH2 | |
| SCHEMBL29759089 | 0.79 | CTSA (0.44) | KCNH2 | |
| SCHEMBL29759256 | 0.77 | ITGB3 (0.41) | PTGER1ITGAVITGB3ITGA2BCASP1 | |
| SCHEMBL24527117 | 0.76 | LRRK2 (0.46) | ALDH1A1KCNH2 | |
| SCHEMBL29742520 | 0.75 | CYP3A4 (0.46) | CYP3A4ALDH1A1KYNUTSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129047-A2 | NOVEL MODULATORS OF THE NMDA RECEPTOR | H. LUNDBECK A/S (DK) | 2022-06-23 | — | — | WO | disclosed |