Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043941 | 0.79 | TDP1 (0.40) | TDP1TSHRALDH1A1RECQLPOLB | |
| SCHEMBL15603514 | 0.78 | TSHR (0.41) | TDP1TSHRALDH1A1RECQLESR1 | |
| SCHEMBL1470831 | 0.75 | NR1H2 (0.53) | TDP1TSHRALDH1A1RECQLPOLB | |
| SCHEMBL4340363 | 0.75 | ESR1 (0.41) | TDP1TSHRALDH1A1RECQLPOLB | |
| SCHEMBL8509750 | 0.75 | ESR1 (0.41) | TDP1TSHRALDH1A1RECQLPOLB | |
| SCHEMBL8863966 | 0.75 | SMN1; SMN2 (0.39) | TSHRALDH1A1NR1H2NR1H3LMNA | |
| SCHEMBL3889886 | 0.74 | NR1H2 (0.50) | TSHRALDH1A1ESR1ESR2NR1H2 | |
| SCHEMBL4182445 | 0.74 | IDO1 (0.38) | ESR1ESR2 | |
| SCHEMBL506540 | 0.70 | NR1H2 (0.33) | TDP1TSHRALDH1A1RECQLPOLB | |
| SCHEMBL10625224 | 0.70 | TDP1 (0.37) | TDP1TSHRALDH1A1RECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634534-B2 | Degradable silyl-containing thermosetting networks | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2023-04-25 | — | — | US | claimed |
| US-11634534-B2 | Degradable silyl-containing thermosetting networks | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2023-04-25 | — | — | US | disclosed |
| US-11401368-B2 | Silyl-containing thermosetting networks and methods of degradation | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2022-08-02 | — | — | US | disclosed |