SCHEMBL4182445

SCHEMBL4182445

SCC[Si](CCS)(CCS)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.38
HDAC3 O15379 4/20 0.32
HDAC4 P56524 4/20 0.32
HDAC1 Q13547 4/20 0.32
HDAC7 Q8WUI4 4/20 0.32
HDAC2 Q92769 4/20 0.32
HDAC10 Q969S8 4/20 0.32
HDAC11 Q96DB2 4/20 0.32
HDAC8 Q9BY41 4/20 0.32
HDAC6 Q9UBN7 4/20 0.32
HDAC9 Q9UKV0 4/20 0.32
HDAC5 Q9UQL6 4/20 0.32
FOLH1 Q04609 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4190206 0.85 HDAC3 (0.39) IDO1HDAC3HDAC4HDAC1HDAC7
SCHEMBL4193671 0.79 IDO1 (0.38) IDO1HDAC3HDAC4HDAC1HDAC7
SCHEMBL29759405 0.74 TDP1 (0.40) ESR1ESR2
SCHEMBL3889886 0.74 NR1H2 (0.50) ESR1ESR2
SCHEMBL11732436 0.73 IDO1 (0.33) IDO1HDAC3HDAC4HDAC1HDAC7
SCHEMBL8684348 0.72 HDAC3 (0.37) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL21748441 0.70 MAOA (0.43)
SCHEMBL3886636 0.70 TSHR (0.38)
SCHEMBL7139123 0.70 HDAC3 (0.39) IDO1HDAC3HDAC4HDAC1HDAC7
SCHEMBL988676 0.69 NR1H2 (0.43) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6507049-B1 Encapsulants for solid state devices GENERAL ELECTRIC COMPANY 2003-01-14 US claimed
WO-2002019440-A1 ENCAPSULANTS FOR SOLID STATE DEVICES GENERAL ELECTRIC COMPANY (US) 2002-03-07 WO claimed
US-5145889-A For light-emitting diodes KABUSHIKI KAISHA TOSHIBA (JP) 1992-09-08 US claimed
US-20090121251-A1 Siloxane-hydantoin copolymer, optoelectronic device encapsulated therewith and method LUMINATION LLC 2009-05-14 US disclosed
US-20080160317-A1 Optoelectronic device GELCORE LLC 2008-07-03 US disclosed
US-20080001140-A1 Optoelectronic device GELCORE LLC 2008-01-03 US disclosed
US-20070299162-A1 Light emitting semiconductor and encapsulant is made from nano-functionalized zirconia; silicone epoxy, epoxy isocyanurate and succinic anhydride, dodecenylsuccinic anhydride, phthalic anhydride curing agent; ancillary curing catalyst, cure modifier, coupling agent, UV, thermal stabilizer GELCORE LLC 2007-12-27 US disclosed
US-20070295983-A1 Optoelectronic device GELCORE LLC 2007-12-27 US disclosed
US-20070295956-A1 Optoelectronic device GELCORE LLC 2007-12-27 US disclosed
EP-1408087-B1 Epoxy-polysiloxane resin compositions, solid state devices encapsulated therewith and method GEN ELECTRIC (US) 2007-10-10 EP disclosed
US-7144763-B2 light emitting diode; curable silicone with pendant epoxy groups, a hydroxyl-containing compound or silicone, anhydride curing agent, ancillary curing catalyst; radiation transparent, UV stability, clear; packaging GENERAL ELECTRIC COMPANY (US) 2006-12-05 US disclosed
US-20030071366-A1 For encapsulating a solid state device, such as a light emitting diode GENERAL ELECTRIC COMPANY 2003-04-17 US disclosed
US-20030071368-A1 Epoxy resin compositions, solid state devices encapsulated therewith and method GENERAL ELECTRIC COMPANY 2003-04-17 US disclosed
US-20030071367-A1 Epoxy resin compositions, solid state devices encapsulated therewith and method GENERAL ELECTRIC COMPANY 2003-04-17 US disclosed
EP-1285938-A1 Epoxy resin encapsulation compositions GENERAL ELECTRIC COMPANY (US) 2003-02-26 EP disclosed
EP-1285939-A1 Epoxy resin compositions and solid state devices encapsulated therewith GENERAL ELECTRIC COMPANY (US) 2003-02-26 EP disclosed
US-6507049-B1 Encapsulants for solid state devices GENERAL ELECTRIC COMPANY 2003-01-14 US disclosed
WO-2002019440-A1 ENCAPSULANTS FOR SOLID STATE DEVICES GENERAL ELECTRIC COMPANY (US) 2002-03-07 WO disclosed
US-5145889-A For light-emitting diodes KABUSHIKI KAISHA TOSHIBA (JP) 1992-09-08 US disclosed
US-4442015-A LIQUID, HYDROLYZABLE ORGANOSILANE Packo, Joseph J. (US) 1984-04-10 US disclosed