Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 10/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | NQO2 | P16083 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3508630 | 1.00 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13436463 | 0.98 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13436465 | 0.94 | MTNR1A (0.88) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13436444 | 0.93 | MTNR1A (0.88) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13436443 | 0.92 | MTNR1A (0.86) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13436479 | 0.90 | MTNR1A (0.83) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13462138 | 0.90 | MTNR1A (0.82) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3589948 | 0.90 | MTNR1A (0.82) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13436478 | 0.90 | MTNR1A (0.81) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13436473 | 0.89 | MTNR1A (0.81) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021574-A1 | MODULATORS OF CIRCADIAN RHYTHMS AND USES THEREOF | The Regents of the University of California (US) | 2022-07-06 | — | — | EP | disclosed |